Exam Master Neuro Practice Exam 2025 - Free Neuro Practice Questions and Study Guide

The feature that strongly suggests a diagnosis of complex regional pain syndrome (CRPS) is sensitivity to touch, also known as allodynia. In patients with CRPS, even light touch or gentle pressure can provoke significant pain, which is a hallmark symptom of the condition. This heightened sensitivity occurs in the affected area, and it reflects the underlying neuroplastic changes and dysfunction in the central and peripheral nervous systems associated with CRPS.

Other symptoms of CRPS can include changes in skin temperature, color, and texture, as well as swelling and joint stiffness. The presence of sensitivity to touch is crucial for differentiating CRPS from other pain syndromes, as it indicates a complex interaction between the nervous system and pain perception.

Localized weakness and persistent numbness may occur in various conditions but do not specifically point to CRPS. Similarly, symmetrical pain can be associated with a range of chronic pain conditions and is not a characteristic feature of CRPS, which typically presents with unilateral pain. Thus, sensitivity to touch is the defining feature that aligns most closely with the diagnosis of complex regional pain syndrome.